EPIDEMIOLOGICAL ANALYSIS AND PROGNOSIS OF MISCARRIAGE IN UKRAINE AND LVIV REGION
ARTICLE PDF (Українська)

Keywords

miscarriage
prognosis
reproductive disorders
prevention of miscarriage
demographic crisis

How to Cite

Gutor, T., & Timchenko, N. (2023). EPIDEMIOLOGICAL ANALYSIS AND PROGNOSIS OF MISCARRIAGE IN UKRAINE AND LVIV REGION. Clinical and Preventive Medicine, (2), 38-44. https://doi.org/10.31612/2616-4868.2(24).2023.06

Abstract

The aim. Substantiation of the prognostic component in the process of developing the model of prevention of miscarriage among the female population of Ukraine.

Materials and methods. A retrospective epidemiological analysis of the miscarriage dynamics among the female population of Ukraine and Lviv region for the period of 2014-2021 was performed, and prognosis of the indicators of this pathology until 2026 was established. The work uses the methods of a systemic approach and structural-logical analysis, medical-statistical analysis , prognostic methodology using exponential smoothing according to the two-parameter Holt method.

Results and discussion. Over the analyzed period from 2014 to 2021, an increase in the index of the ratio of the total rate of miscarriage to the total number of pregnancies (cases of miscarriage per 100 pregnancies) from 5.50 in 2014 to 6.22 in 2021 in Ukraine and from 3.57 to 4.72 in Lviv region, respectively, was noted. In order to predict the ratio of miscarriages to the total number of pregnancies we have chosen the exponential smoothing method according to the two-parameter Holt method. In our opinion, this indicator will be the least dependent on the impact of war and COVID-19 pandemic. 

All other conditions remaining unchanged, the prognosis results predict that in 2026, the ratio of miscarriage to the total number of pregnancies in Ukraine will amount to 6.37 cases of miscarriage per 100 pregnancies, and 5.38 cases of miscarriage per 100 pregnancies in Lviv region.

Conclusions.

Analysis of the dynamic indicators of the ratio of stillbirths to the total number of pregnancies over the analyzed 8-year period both in Ukraine and in Lviv region showed a trend towards annual growth of this index.

A worsening of the demographic situation according to the results of the study, as well as the likely development of a demographic crisis in connection with the state of war in Ukraine and the mass migration of the female population provoked by the war, requires searching for all possible ways to prevent miscarriage and take into account this prognostic-negative trend in the development of preventive programs.

https://doi.org/10.31612/2616-4868.2(24).2023.06
ARTICLE PDF (Українська)

References

Pro vnesennya zmin do nakazu MOZ Ukrayiny vid 15 hrudnya 2003 roku N 582 "Pro zatverdzhennya klinichnykh protokoliv z akushersʹkoyi ta hinekolohichnoyi dopomohy", nakazu MOZ vid 31.12.2004 roku N 676 "Pro zatverdzhennya klinichnykh protokoliv z akushersʹkoyi ta hinekolohichnoyi dopomohy": N a k a z 03.11.2008 № 624 [On amendments to the order of the Ministry of Health of Ukraine dated December 15, 2003 No. 582 "On the approval of clinical protocols for obstetric and gynecological care", the order of the Ministry of Health of Ukraine dated December 31, 2004 No. 676 "On the approval of clinical protocols for obstetric and gynecological care": and from 03.11.2008 No. 624]. Available from: https://zakononline.com.ua/documents/show/33936___485938

Vorobyova, I.I., Zhyvetsʹka-Denysova, A.A., Tkachenko, V.B., Rudakova, N.V. (2017). Nevynoshuvannya vahitnosti: suchasni pohlyady na problemu: ohlyad literatury [Miscarriage: modern views on the problem: literature review]. Women's health, 3(119), 113-117.

Bagkou Dimakou, Danai et al. (2022). Understanding human immunity in idiopathic recurrent pregnancy loss. European journal of obstetrics, gynecology, and reproductive biology, 270, 17-29. doi:10.1016/j.ejogrb.2021.12.024

Rossen, L.M., Ahrens, K.A., Branum, A.M. (2018). Trends in Risk of Pregnancy Loss Among US Women, 1990-2011. Paediatr Perinat Epidemiol., Jan. 32(1), 19-29. doi: 10.1111/ppe.12417.

Huchon, C. et al. (2016). Pregnancy loss: French clinical practice guidelines. European journal of obstetrics, gynecology, and reproductive biology, 201, 18-26. doi:10.1016/j.ejogrb.2016.02.015.

Torchin, H., Ancel, P.Y. (2016). Épidémiologie et facteurs de risque de la prématurité [Epidemiology and risk factors of preterm birth]. J Gynecol Obstet Biol Reprod (Paris), 45(10), 1213-1230. doi: 10.1016/j.jgyn.2016.09.013.

Tietzmann, M.R., Teichmann, P.D.V., Vilanova, C.S., Goldani, M.Z., Silva, C.H.D. (2020). Risk Factors for Neonatal Mortality in Preterm Newborns in The Extreme South of Brazil. Sci Rep., 29. 10(1), 7252. doi: 10.1038/s41598-020-64357-x.

Torchin, H., Ancel, P.Y., Jarreau, P.H., Goffinet, F. (2015). Épidémiologie de la prématurité: prévalence, évolution, devenir des enfants [Epidemiology of preterm birth: Prevalence, recent trends, short- and long-term outcomes]. J Gynecol Obstet Biol Reprod (Paris), Oct. 44(8), 723-31. doi: 10.1016/j.jgyn.2015.06.010.

Lorthe E., Torchin H., Delorme P. (2018). Preterm premature rupture of membranes at 22-25 weeks' gestation: perinatal and 2-year outcomes within a national population-based study (EPIPAGE-2). Am J Obstet Gynecol., 219(3), 298.e1-298.e14. doi: 10.1016/j.ajog.2018.05.029.

Rodych, O. Y. U., Hutor, T. H. (2014). Metodychni osnovy protsesu prohnozuvannya kilʹkosti narodzhenykh ditey z maloyu masoyu tila [Methodological foundations of the process of forecasting the number of children born with low body weight]. Actual problems of clinical and preventive medicine, 2, 2-3, 18-22.

Kumar Vasantha, H. S. (2022). Cardiovascular Morbidities in Adults Born Preterm: Getting to the Heart of the Matter!. Children, 9, 12, 1843. 28. doi:10.3390/children9121843.

Timchenko, N. F., Gutor, T.G. (2022). Dynamics of miscarriage among the female population of fertile age in Ukraine and in Lviv region in 2014-2021. Acta Medica Leopoliensia, 28(3-4),72-86.

Statystychni dani Tsentru medychnoyi statystyky MOZ Ukrayiny [Statistical data of the Center for Medical Statistics of the Ministry of Health of Ukraine]. Available from : http://medstat.gov.ua/ukr/statdanMMXIX.html

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.