@article{Samoilenko_Syniachenko_Syniachenko_Pylypenko_2018, title={Endovascular laser coagulation of the lower limbs varicose veins: effectiveness and optimization}, url={http://cp-medical.com/index.php/journal/article/view/20}, DOI={10.31612/2616-4868.2-5.2018.05}, abstractNote={<p><strong>The purpose </strong>of the work is to assess the efficiency of endovascular laser coagulation (EVLC) of varicose vein disease of lower limb and to define the ways of optimization of such treatment.</p> <p><strong>Material and methods. </strong>Out of 263 patients isolated EVLC was performed in 33.8% of the cases, with crossectomy and chemical sclerotherapy by sclerovein or fibro-vein – in 8.0%, with sclerotherapy without crossectomy – in 58.2%. EVLC was carried out by means of the device “Fotonika-Lika-Surgeon” (Ukraine).</p> <p><strong>Results. </strong>In a month, a considerable improvement was noted in 39.9% of patients after EVLC, and later in a half a year – at 93.9%, at the same time the risk factors of the lower efficiency of the operation were the male and advanced age of the patients, high arterial blood pressure, the narrowing of the femoral arteries and the presence of comorbide gonarthrosis, within the first 4 weeks from the time of the operation the results of the treatment were closely connected with the changes of initial superficial adsorptive and rheological viscose properties of venous blood, whereas later on they depend on the condition of endothelial function of the vessels (the indicators of superficial viscosity, thromboxane-A2 and prostacyclin can have the predictive value), and the best effect is reached after holding of sclerotherapy conjoint with EVLC and the prescription of rivaroxaban within the first two weeks, besides, low-molecular heparins and cyclo-3-fort.</p&gt;}, number={2-3}, journal={Clinical and Preventive Medicine}, author={Samoilenko, G. Ye. and Syniachenko, O. V. and Syniachenko, Yu. O. and Pylypenko, R. V.}, year={2018}, month={Oct.}, pages={43-49} }