Анотація
Aim: The aim of the study was to determine whether certain cognitive domains exist in the assessment of cognitive functions in HD patients, patients with hypothyroidism and HD patients with concomitant hypothyroidism.
Material and methods: The patients were divided into 3 groups according to nosology: Group I – 21 patients with hypertensive disease (HD); Group II – 18 patients with hypothyroidism, Group III – 19 hypertensive patients with concomitant hypothyroidism.
Results: It was revealed that patients with HD had a decrease in memory according to the test proposed by A.R. Luria for learning 10 words, (p<0.05), as well as Digit span from Mattisse scale, (p<0.05). In patients with hypothyroidism, a short span of attention was revealed, according to the method of “Selectivity of attention” (G. Munsterberg test), (p<0.05). The analysis of the results showed that considering the interaction of factors (HD and hypothyroidism), the most affected cognitive domains are memory, executive functions and optical-spatial functions, respectively, (p<0.05).
Conclusions: To diagnose CI in patients with HD who have problems with the domain of cognitive function memory, it is advisable to use a test for learning 10 words according to the method proposed by A.R. Luria and Digit span from Mattisse scale. In patients with hypothyroidism, attention and executive functions should be determined using the Schulte Tables and the “Selectivity of Attention” method (G. Munsterberg test). With the combined pathology, HD patients with a concomitant hypothyroidism should use Schulte Tables, test for learning 10 words by A.R. Luria and Clock Drawing Test.
Посилання
Koval, S. M., Snigurskaya, I. O. (2010). Peculiarities of the clinical course and differentiated approaches to the treatment of arterial hypertension in patients with concomitant diseases of the internal organs. Arterial hypertension, 6(14 ), 36-41.
Lesiv, M. I. (2017). Cognitive-Mnestic Functions in Patients Suffering from Hypertensive Disease with Hypothyroidism Comorbidity. NTH Pulse, 7(43), 56-61.
Zakharov, VV. (2011). Neuropsychological tests. Necessity and possibility of application. Сonsilium-medicum, 13, 2, 98 –106.
O’Brien, J. T. (2017). Clinical practice with anti-dementiadrugs: A revised (third) consensusst at ement from the British Association for Psychopharmacolog. Journal of Psychopharmacology, 31(2), 147–68.
Forette F., Seux M. L., Staussen J. A. [et al.]. (2002). Forette Syst-Eurstudy (Systolic hypertension in Europe Investigators. The prevention of dementia with antihypertensive treatment: new evidence from the Systolic Hypertension in Europe (Syst-Eur) study. Arch. Intern.Med., 162, 661-3.
McGuinness B., Todd S., Passmore P., Bullock R. (2009). Blood pressure lowering in patients without prior cerebrovascular disease for prevention of cognitive impairment and dementia. Cochrane Database of Systematic Reviews, 4.
Trenkwalder, P. (2006). The study on Cognition and Prognosis in the Elderly (SCOPE) recent analyses. J. Hypertension, 24, 107-14.
Siegmund W. (2004). Replacement therapy with T4 plus T3 / Blackwell Publishing Ltd. Clinical Endocrinology, 60, 750–7.
Luca Persania [et al.] (2018). Guidelines on the Diagnosis and Management of Central Hypothyroidism: European Thyroid Association. Thyroid, (7), 225–37.
Petrova, M. M., Schneider, N.A., Eremina, O.V. (2008). Characteristics of cognitive disorders in patients with arterial hypertension. Cardiovascular therapy and prevention, (2), 23–6.
Kovalenko, O. E., Litvin, O.V. (2011). Peculiarities of hypertensive encephalopathy in patients with hypothyroidism. Ukrainian Medical Almanac, 14 (6), 103.
Vinall, M. (2016). Digest of the Congress of the European Society of Cardiology. Arterial hypertension, 6(50), 81-98.
Britov, A.N., Bystrova, M.M. (2010). Resistant arterial hypertension: modern approaches to diagnosis and treatment. Rational Pharmacotherapy in Cardiology, 6(2), 206-11.
Lesiv, M.I. (2020). Cognitive Functions in Patients Suffering from Hypertension and Hypothyroidism with Retrospective Evaluation of the Control of Disease Compensation. Medicni perspektivi, XXV, 1.
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