TY - JOUR AU - V.V. Paramonov AU - І.S. Dyagil PY - 2021/06/25 Y2 - 2024/03/29 TI - CUMULATIVE INCIDENCE OF LYMPHOID AND MYELOID LEUKEMIAS IN DIFFERENT REGIONS OF THE CHERKASSY REGION IN 2001 AND 2014 JF - Clinical and Preventive Medicine JA - Clin. and prev. med. VL - IS - 2 SE - Research DO - 10.31612/2616-4868.2(16).2021.06 UR - https://cp-medical.com/index.php/journal/article/view/162 AB - The purpose - to carry out comparison of the cumulative morbidity on the lymphoid and myeloid leukemia on relatively clean and contaminated regions of the Cherkassy region for 2001 and 2014.Materials and methods. The incidence was determined in regions A (relatively clean), B (radioactive contaminated), C (chemically contaminated) and D (radioactive and chemical contaminated) per 100 thousand population, which was registered during the All-Ukrainian census conducted in 2001, and in 2014 according to the published data of the State Statistical Service of Ukraine.Results. In 2001, in the radioactive contaminated region of Cherkassy oblast, there was a 2.46-fold (p = 0.024) higher incidence of myeloid leukemias alone (5.30; 3.03-8.33 vs. 2.15; 0.66-3.64 per 100 thousand population, respectively). Instead, in the area contaminated with chemical factors, the prevalence of lymphoid (acute and chronic) was determined (7.12; 1.84 - 12.39 vs. 2.69; 1.02 - 4.35 per 100 thousand population, respectively) and myeloid (6.10; 1.22 - 10.99 vs. 2.15; 0.66 - 3.64 per 100 thousand population, respectively) leukemia, compared with relatively clean regions. According to 2001 data, who living in a chemical contaminated region, the risk of cumulative morbidity for acute and chronic lymphoid and myeloid leukemias is 3.30 (p = 0.014) and 2.83 (p = 0.043), respectively.In 2014, no increase in the level of cumulative incidence of these hematological neoplasms was detected between the clean and contaminated regions of Cherkassy oblast.Conclusions. It was proved that the radiation factor in 2001 increased the probability of growth the cumulative incidence only for myeloid leukemias, and chemical contamination - for both myeloid and lymphoid leukemias. In 2014, there was no increase in the level of cumulative incidence of certain hematological diseases between clean and contaminated regions of Cherkasy oblast. ER -